Potomac Grove Clinical Research Center Clinical Research Center

Even after you have recovered from a depression, it is very common to have two or more further episodes during your life. These episodes may not respond as completely to the treatments that previously got you well.

If this describes your situation, you may qualify to participate in new study aimed at finding the most effective dosage of a medication that not only gets you well but keeps you well.

We are conducting a clinical research study to better understand the effects of an investigational medication which has the potential to relieve this problem when compared to an approved medication. You are eligible to take part in this study if you meet the following requirements:

• Age 18-75 and diagnosed with having a Recurrent Major Depressive Episode Been depressed for more than 8 weeks but less than 18 months

• Have had at least two other Major Depressive Episode in your life

• Currently taking one antidepressant for a minimum of 6 weeks, such as:

Celexa ® (citalopram)
Lexapro* ( escitalopram)
Paxil ® (paroxetine and extended release), or Zoloft ® (sertaline)
Cymbalta*(duloxetine)
Remeron* (Mirtazapine)
Effexor* (venlafaxene and extended release)
Prestiq*
Wellbutrin*(buproprion and extended release)
Prozac* (fluoxetine)

• The depression continues even with medication, and while you may be better, you are not well

What are the benefits of participation in this study?

While the study is taking place you will receive at no charge :

— a psychiatric evaluation
— medication
–medication monitoring
— payment to cover time and travel expenses
— an opportunity to try a new treatment for depression — while receiving treatment for yourself, you will also benefit others by increasing understanding of effective treatments for depression

If you would like to know more about this study, call our Research Coordinator, Karen Phinney, R.N., 301-258-8858 or email clinicalstudy@verizon.net. [LINK] She will answer your questions and help you determine whether this study might be appropriate for you.